Can Vitamin A derivatives, including retinol, rapidly break down when exposed to the sun and air. original sound. At the wrong time: The application process of both products is fairly similar, but the main difference in how to use retinol vs vitamin C is the best time of day to apply them. "Vitamin C and retinol can be used together, but we wouldn't advise using them at the same time of day unless the product in question has been carefully formulated," explains Dan Isaacs, Director of Research at Medik8. What Vitamins Should Not Be Taken Together? - MedicineNet These Are The Skincare Ingredients You Should Never Mix Do Retinol and Vitamin C Interact Well If Applied Together? However, it’s important to stick to just one and not to layer acids – this will irritate skin and make the scars more inflamed. Both retinol and vitamin C provide a multitude of skin health benefits, and they can be an effective system for reversing aging damage when used together. Like tretinoin, retinol encourages skin cell turnover; this new skin is delicate and should not be exposed to the sun. NATURAL AND EFFECTIVE. Mixing it with acids can cause dryness and irritation and damage the skin’s moisture barrier, and together they’ll also increase skin’s sensitivity to the sun, meaning you’re at a much higher risk of burning and UV damage. You're using too much retinol. … Don't Mix: Retinol with vitamin C, benzoyl peroxide, and AHA/BHA acids. Retinol Rule #3 – Soothe Your Skin. Richest sources are nuts, spinach, whole grains, olive oil, and sunflower oil. Mixing it with acids can cause … vitamin.